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B-cell specific ablation of ChAT increases the mortality of mice subjected to partial hepatectomy compared to their wildtype counterpart, due to dysregulation of 7nAChR expressing Kupffer cells and CD8 + T cells, limiting their regenerative capacity and producing harmful IFN-, respectively (112)

Macrophage extracellular traps promote tumor-like biologic behaviors of fibroblast-like synoviocytes through cgas-mediated pi3k/akt signaling pathway in patients with rheumatoid arthritis